Showed enhanced glycemia and SBP versus premenopausal, whilst postmenopausal diabetic females

Showed improved glycemia and SBP versus premenopausal, though postmenopausal diabetic females presented elevated SBP without having alterations on BMI or WC when compared with premenopausal diabetic patients (Table two and Figure 2D).Table 1 Information from the diabetic population and age and gender-matched controlsControl group Parameters Age (years) Gender ( M/ F) BMI (Kg/m2) WC (cm) SBP (mmHg) DBP (mmHg) Glycemia (mmol/L) HbA1c ( ) Total-c (mmol/L) TGs (mmol/L) LDL-c (mmol/L) Ox-LDL (U/L) Non-HDL-c (mmol/L) PON1 activity Male (n = 39) 59.97 1.02 52.70 27.89 0.72 101.32 1.75 145.28 3.08 87.ten 1.54 5.58 0.08 — five.71 0.15 1.28 0.08 three.70 0.15 52.65 two.60 4.28 0.15 519.66 18.63 Female (n = 35) 54.71 1.68 47.30 27.09 0.71 92.26 1.96 143.74 three.98 87.76 two.06 5.12 0.09 — 5.30 0.14 1.08 0.06 3.36 0.13 33.23 1.92 3.86 0.14 449.05 21.66 P 0.one hundred — 0.704 0.003 0.010 0.654 0.000 — 0.121 0.118 0.222 0.000 0.110 0.034 Male (n = 57) 58.88 1.34 51.82 30.37 0.65 110.36 1.70 136.86 2.95 73.54 1.69 9.70 0.48 8.13 0.25 four.75 0.15 1.85 0.15 two.69 0.14 32.58 1.78 three.50 0.16 426.01 20.27 Diabetic group Female (n = 53) 60.49 1.42 48.18 30.12 0.67 104.02 two.05 137.53 3.61 72.74 1.77 10.69 0.59 9.20 0.30 4.89 0.15 1.99 0.15 two.69 0.14 32.42 1.84 three.56 0.16 490.17 30.31 P 0.524 — 0.788 0.020 0.942 0.745 0.191 0.007 0.526 0.406 0.996 1.000 0.635 0.077 Diabetic vs handle (P) Male 0.453 — 0.013 0.000 0.002 0.000 0.000 — 0.000 0.002 0.000 0.000 0.004 0.004 Female 0.013 — 0.002 0.000 0.000 0.000 0.000 — 0.129 0.000 0.012 0.401 0.257 0.Outcomes are presented as media SEM. Independent samples T-test and Mann hitney test for normalized and non-normalized samples, respectively. P adjusted for age and BMI (ANCOVA) when sufficient (when p0.05): for age when comparing female diabetic vs female manage subjects; for BMI when comparing diabetic vs manage (each for male and for female). BMI, body mass index; HbA1c, glycated hemoglobin; SBP, systolic blood stress; DBP, diastolic blood pressure; LDL-c, low-density lipoprotein cholesterol; Ox-LDL, oxidized low-density lipoprotein; TGs, triglycerides; Total-c, total cholesterol; WC, waist circumference.Methyl laurate Purity Mascarenhas-Melo et al.Sabizabulin supplier Cardiovascular Diabetology 2013, 12:61 http://www.PMID:23443926 cardiab/content/12/1/Page five ofTable two Information from the female diabetic population and age-matched controls: menopause influenceFemale manage group Parameters Age (years) BMI (Kg/m ) WC (cm) SBP (mmHg) DBP (mmHg) Glycemia (mmol/L) HbA1c ( ) Total-c (mmol/L) TGs (mmol/L) LDL-c (mmol/L) Ox-LDL (U/L) Non-HDL-c (mmol/L) PON1 activityFemale diabetic group P 0.000 0.472 0.575 0.004 0.175 0.038 — 0.364 0.455 0.514 0.044 0.390 Pre-M (n = 8) Post-M (n = 45) 43.88 1.29 29.43 2.44 one hundred.57 four.93 120.38 7.22 72.25 three.14 10.80 1.65 9.03 1.08 4.68 0.44 1.51 0.31 two.71 0.35 34.83 .58 three.36 0.45 63.44 1.20 30.24 0.67 104.66 2.27 140.58 three.91 72.82 two.02 ten.67 0.64 9.23 0.30 4.93 0.16 2.08 0.17 2.69 0.15 31.89 1.61 three.60 0.17 498.39 35.22 P 0.000 0.578 0.081 0.048 0.519 0.832 0.477 0.725 0.467 0.997 0.993 0.781 0.Diabetic vs manage (P) Pre-menopausal Post- menopausal 0.349 0.221 0.103 0.187 0.027 0.000 — 0.313 0.066 0.164 0.897 0.236 0.527 0.345 0.013 0.000 0.113 0.000 0.000 — 0.090 0.003 0.007 0.339 0.243 0.Pre-M (n = 16) Post-M (n = 19) 45.63 1.12 26.93 1.21 91.38 2.86 132.69 five.62 84.25 three.20 four.92 0.ten — five.08 0.16 1.02 0.08 3.21 0.17 29.13 1.76 3.68 0.17 415.66 26.78 62.37 1.35 27.21 0.85 93.06 two.75 153.56 four.61 90.89 2.52 five.31 0.14 — five.48 0.21 1.13 0.ten 3.47 0.19 36.46 2.98 4.01 0.20 477.1732.0.420.