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The 14-three-3 protein household has been shown to physically interact with a broad variety of diverse proteins (about a hundred), which include enzymes, cytoskeletal and structural proteins, kinases, membrane proteins, and transcription components fourteen-three-3 proteins

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As demonstrated in the left panel of Figure 4A, upon immunoprecipitating myc-fourteen-three-3h with the...
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The molecular dynamic simulation showed that the NGR motif had a sturdy propensity to type b-turn (Gly3-Arg4) in linear peptides, and the disulfide bridge constraint was essential for stabilizing the bent conformation and for increasing the tumor focusing on efficiency

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When the LLC tumor volume arrived at about 30000 mm3, ninety nine mTc-labeled hPK5...
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Although we cannot be specific at this point that destabilization of Sic1 in ime2D cells takes place by way of the identical course of action as in WT cells, our benefits plainly suggest that the Sic1 steady point out stage can be lowered considerably in an Ime2-unbiased manner

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CACAAAA (MSE) was identified to be important particularly at six hrs, although sequences intently...