Product Name :
Rabbit anti-PATL1 Polyclonal Antibody(C-term)
Synonym :
Protein PAT1 homolog 1; PAT1-like protein 1; Protein PAT1 homolog b; Pat1b; hPat1b; PATL1
Host :
Rabbit
Species Reactivity:
Human
Specificity :
This PATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human PATL1.
Predicted Reactivity:
Mouse, Rat
Applications :
WB~~1:1000IHC-P~~1:50~100FC~~1:10~50
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Microbiology;Others
Background :
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
UniProt :
Q86TB9
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym Protein PAT1 homolog 1; PAT1-like protein 1; Protein PAT1 homolog b; Pat1b; hPat1b; PATL1 |Host Rabbit |Specificity This PATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human PATL1. |Species Reactivity Human |Predicted Reactivity Mouse, Rat |Applications WB~~1:1000IHC-P~~1:50~100FC~~1:10~50 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Microbiology;Others |Target |Background RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV). |Cellular localization Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle. Note=Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus |UniProt Q86TB9 |References |References Scheller, N., et al. Biochim. Biophys. Acta 1773(12):1786-1792(2007)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-PATL1 Polyclonal Antibody(C-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
646502-53-6 web 13411-16-0 Biological Activity PMID:29083803 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
