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Fibroblasts generate the bulk of the extracellular matrix (ECM) as effectively as degradative enzymes, this kind of as matrix metalloproteases (MMPs), which control and remodel the myocardial ECM, as well as advertise collagen synthesis and turnover

The pCMV6yc-DDK and pCMV6yc-DDK-ZNF703 plasmids have been acquired from Origene Organization. For secure transfections,...